The dub title of the new Pokémon animé season has been revealed, via the Pokémon HeartGold and SoulSilver official website. The new series will simply be called "Pokémon Black and White", the names of the fifth generation games.
In Japan, it is called "Pokemon:Best Wishes", a play on the first initials of the games, as well as how the romaji for "Wishes" (roughly "Uisshus") resembles the Japanese name of the Unova Region, "Isshu".

Source(s): [ http://www.pokemongoldsilver.com/us/#/news/ashspikachu ]

Awww, I was wishing they'd keep Best Wishes. Oh well, I suppose it won't hurt. :I